公共资源库 / 计算器

PCE2013 · 历史模型

重现 2013 年历史方程，估计十年内首次非致死性心肌梗死、冠心病死亡或致死性／非致死性卒中。不估计心力衰竭、终生风险或治疗效果。

透明计算

请核对适用人群、单位和版本。结果展示公式或分类，不自动作出治疗决定。

正在准备表单…

核对方法
填写数据
核对结果

方法 · 适用限制

PCE2013 · 附录 4 表 A/B 中发表的系数；历史模型

人群分类是来源中的两种历史美国分类；不得默认为其他人群替代模型。年龄：40–79 岁；总胆固醇：130–320 mg/dL；HDL：20–100 mg/dL；收缩压：90–200 mmHg。三个检验／血压范围是旧版官方估计器的输入约定。须明确回答病史及确认项；未知回答或排除条件不产生估计。 ACC 说明，PCE 得出的十年风险已不再受到现行临床政策／指南支持。本实现是历史研究候选，不是 PREVENT、治疗建议或临床验证。一个已发表的白人男性示例仍有差异：用发表系数计算并舍入为 5.4%，但表中印为 5.3%。未更改系数来掩盖差异。尚未完成分发许可及临床／专业审核。

必填字段: 0/17 已填写

请填写所有必填字段。选填字段已标明。

已发表方程使用的性别必填

模型推导人群组别必填

年龄必填岁 · 范围 40–79

总胆固醇必填mg/dL · 范围 130–320

HDL 胆固醇必填mg/dL · 范围 20–100

收缩压必填mmHg · 范围 90–200

目前接受降压治疗？必填

目前吸烟？必填

糖尿病？必填

既往心肌梗死？必填

既往卒中？必填

既往心力衰竭？必填

既往经皮冠状动脉介入治疗？必填

既往冠状动脉旁路移植术？必填

既往心房颤动？必填

已确认基线评估时表面健康的状态？必填

已确认将此历史模型用于研究？必填

此表单不会在浏览器中保存数据。

使用条件

请在原始资料中核对适用人群、单位、纳入和排除标准及版本。单个结果不能确立诊断、决定出院或开具处方。

已记录参数

已发表方程使用的性别
模型推导人群组别
年龄 · 岁
总胆固醇 · mg/dL
HDL 胆固醇 · mg/dL
收缩压 · mmHg
目前接受降压治疗？
目前吸烟？
糖尿病？
既往心肌梗死？
既往卒中？
既往心力衰竭？
既往经皮冠状动脉介入治疗？
既往冠状动脉旁路移植术？
既往心房颤动？
已确认基线评估时表面健康的状态？
已确认将此历史模型用于研究？

20/20 参考案例已核对. 数值测试不等于临床验证。

来源与文档

已记录的公式

转录自来源或已记录的修订，不构成临床建议。

10 年概率 = 1 − S₀^{exp(ΣβX − 均值)}；百分比 = 100 × 概率。X 使用发表的人群／性别列中的自然对数和交互项。保留发表系数的精度；显示一位小数不改变原始结果。

参考文献

标识符： acc-cvd-risk

临床内容的原始语言：巴西葡萄牙语。

方法版本

PCE2013 · 附录 4 表 A/B 中发表的系数；历史模型

ELUCENIA PCE2013 published-coefficient historical research implementation; adapter R8

文献版本用于标识来源，其本身不能证明公式完全符合来源或已获临床批准。

已核对的合成案例 (20)

用于核对实现的合成案例，不含患者数据。

案例 1

reference-001

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔白人
年龄: 55 岁
总胆固醇: 213 mg/dL
HDL 胆固醇: 50 mg/dL
收缩压: 120 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicWhite",
  "ageYears": 55,
  "totalCholesterolMgDl": 213,
  "hdlCholesterolMgDl": 50,
  "systolicBpMmHg": 120,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 2.052229820249467
}

实际结果

{
  "linearPredictor": -29.676672052893,
  "meanPredictorSum": -29.18,
  "baselineSurvival": 0.9665,
  "centeredPredictor": -0.4966720528930004,
  "relativeHazard": 0.6085525241297984,
  "survivalLog": -0.02073580673925355,
  "tenYearProbability": 0.020522298202495015,
  "tenYearPercent": 2.0522298202495017,
  "terms": [
    {
      "name": "age",
      "coefficient": -29.799,
      "feature": 4.007333185232471,
      "product": -119.41452158674241
    },
    {
      "name": "age2",
      "coefficient": 4.884,
      "feature": 16.058719257465423,
      "product": 78.43078485346113
    },
    {
      "name": "tc",
      "coefficient": 13.54,
      "feature": 5.3612921657094255,
      "product": 72.59189592370562
    },
    {
      "name": "ageTc",
      "coefficient": -3.114,
      "feature": 21.484484011374246,
      "product": -66.9026832114194
    },
    {
      "name": "hdl",
      "coefficient": -13.578,
      "feature": 3.912023005428146,
      "product": -53.11744836770336
    },
    {
      "name": "ageHdl",
      "coefficient": 3.149,
      "feature": 15.676779611045077,
      "product": 49.36617899518095
    },
    {
      "name": "sbpT",
      "coefficient": 2.019,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.957,
      "feature": 4.787491742782046,
      "product": 9.369121340624464
    },
    {
      "name": "smoke",
      "coefficient": 7.574,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.665,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.661,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 2

reference-002

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔白人
年龄: 40 岁
总胆固醇: 130 mg/dL
HDL 胆固醇: 100 mg/dL
收缩压: 90 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicWhite",
  "ageYears": 40,
  "totalCholesterolMgDl": 130,
  "hdlCholesterolMgDl": 100,
  "systolicBpMmHg": 90,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 0.03709739617920835
}

实际结果

{
  "linearPredictor": -33.69997193998835,
  "meanPredictorSum": -29.18,
  "baselineSurvival": 0.9665,
  "centeredPredictor": -4.519971939988352,
  "relativeHazard": 0.010889329218972276,
  "survivalLog": -0.00037104278965500624,
  "tenYearProbability": 0.00037097396179208605,
  "tenYearPercent": 0.037097396179208604,
  "terms": [
    {
      "name": "age",
      "coefficient": -29.799,
      "feature": 3.6888794541139363,
      "product": -109.92491885314118
    },
    {
      "name": "age2",
      "coefficient": 4.884,
      "feature": 13.607831626983932,
      "product": 66.46064966618952
    },
    {
      "name": "tc",
      "coefficient": 13.54,
      "feature": 4.867534450455582,
      "product": 65.90641645916858
    },
    {
      "name": "ageTc",
      "coefficient": -3.114,
      "feature": 17.955747826477367,
      "product": -55.91419873165052
    },
    {
      "name": "hdl",
      "coefficient": -13.578,
      "feature": 4.605170185988092,
      "product": -62.529000785346305
    },
    {
      "name": "ageHdl",
      "coefficient": 3.149,
      "feature": 16.987917681789526,
      "product": 53.49495277995522
    },
    {
      "name": "sbpT",
      "coefficient": 2.019,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.957,
      "feature": 4.499809670330265,
      "product": 8.806127524836329
    },
    {
      "name": "smoke",
      "coefficient": 7.574,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.665,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.661,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 3

reference-003

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔白人
年龄: 79 岁
总胆固醇: 320 mg/dL
HDL 胆固醇: 20 mg/dL
收缩压: 200 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicWhite",
  "ageYears": 79,
  "totalCholesterolMgDl": 320,
  "hdlCholesterolMgDl": 20,
  "systolicBpMmHg": 200,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 85.51261878486854
}

实际结果

{
  "linearPredictor": -25.142278849018528,
  "meanPredictorSum": -29.18,
  "baselineSurvival": 0.9665,
  "centeredPredictor": 4.037721150981472,
  "relativeHazard": 56.69699159186172,
  "survivalLog": -1.931892176483967,
  "tenYearProbability": 0.8551261878486882,
  "tenYearPercent": 85.51261878486882,
  "terms": [
    {
      "name": "age",
      "coefficient": -29.799,
      "feature": 4.3694478524670215,
      "product": -130.20517655566476
    },
    {
      "name": "age2",
      "coefficient": 4.884,
      "feature": 19.092074535428665,
      "product": 93.24569203103361
    },
    {
      "name": "tc",
      "coefficient": 13.54,
      "feature": 5.768320995793772,
      "product": 78.10306628304767
    },
    {
      "name": "ageTc",
      "coefficient": -3.114,
      "feature": 25.204377787411527,
      "product": -78.4864324299995
    },
    {
      "name": "hdl",
      "coefficient": -13.578,
      "feature": 2.995732273553991,
      "product": -40.67605281031609
    },
    {
      "name": "ageHdl",
      "coefficient": 3.149,
      "feature": 13.089695949246632,
      "product": 41.21945254417764
    },
    {
      "name": "sbpT",
      "coefficient": 2.019,
      "feature": 5.298317366548036,
      "product": 10.697302763060486
    },
    {
      "name": "sbpU",
      "coefficient": 1.957,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 7.574,
      "feature": 1,
      "product": 7.574
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.665,
      "feature": 4.3694478524670215,
      "product": -7.275130674357591
    },
    {
      "name": "diabetes",
      "coefficient": 0.661,
      "feature": 1,
      "product": 0.661
    }
  ]
}

案例 4

reference-004

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔白人
年龄: 53.25 岁
总胆固醇: 197.5 mg/dL
HDL 胆固醇: 42.5 mg/dL
收缩压: 137.25 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicWhite",
  "ageYears": 53.25,
  "totalCholesterolMgDl": 197.5,
  "hdlCholesterolMgDl": 42.5,
  "systolicBpMmHg": 137.25,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 8.48219790671467
}

实际结果

{
  "linearPredictor": -28.223988350587522,
  "meanPredictorSum": -29.18,
  "baselineSurvival": 0.9665,
  "centeredPredictor": 0.9560116494124777,
  "relativeHazard": 2.6013008567211022,
  "survivalLog": -0.08863667423408561,
  "tenYearProbability": 0.08482197906714718,
  "tenYearPercent": 8.482197906714719,
  "terms": [
    {
      "name": "age",
      "coefficient": -29.799,
      "feature": 3.9749978045895347,
      "product": -118.45095957896355
    },
    {
      "name": "age2",
      "coefficient": 4.884,
      "feature": 15.800607546491621,
      "product": 77.17016725706509
    },
    {
      "name": "tc",
      "coefficient": 13.54,
      "feature": 5.285738584341177,
      "product": 71.56890043197953
    },
    {
      "name": "ageTc",
      "coefficient": -3.114,
      "feature": 21.01079926839037,
      "product": -65.42762892176762
    },
    {
      "name": "hdl",
      "coefficient": -13.578,
      "feature": 3.7495040759303713,
      "product": -50.910766342982576
    },
    {
      "name": "ageHdl",
      "coefficient": 3.149,
      "feature": 14.904270470122738,
      "product": 46.9335477104165
    },
    {
      "name": "sbpT",
      "coefficient": 2.019,
      "feature": 4.92180408038964,
      "product": 9.937122438306684
    },
    {
      "name": "sbpU",
      "coefficient": 1.957,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 7.574,
      "feature": 1,
      "product": 7.574
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.665,
      "feature": 3.9749978045895347,
      "product": -6.6183713446415755
    },
    {
      "name": "diabetes",
      "coefficient": 0.661,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 5

reference-005

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔白人
年龄: 68 岁
总胆固醇: 245 mg/dL
HDL 胆固醇: 36 mg/dL
收缩压: 162 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicWhite",
  "ageYears": 68,
  "totalCholesterolMgDl": 245,
  "hdlCholesterolMgDl": 36,
  "systolicBpMmHg": 162,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 25.963017731680814
}

实际结果

{
  "linearPredictor": -27.002735421315645,
  "meanPredictorSum": -29.18,
  "baselineSurvival": 0.9665,
  "centeredPredictor": 2.1772645786843547,
  "relativeHazard": 8.822140950234154,
  "survivalLog": -0.3006054572398618,
  "tenYearProbability": 0.2596301773168104,
  "tenYearPercent": 25.963017731681038,
  "terms": [
    {
      "name": "age",
      "coefficient": -29.799,
      "feature": 4.219507705176107,
      "product": -125.73711010654281
    },
    {
      "name": "age2",
      "coefficient": 4.884,
      "feature": 17.804245274040536,
      "product": 86.95593391841399
    },
    {
      "name": "tc",
      "coefficient": 13.54,
      "feature": 5.501258210544727,
      "product": 74.48703617077561
    },
    {
      "name": "ageTc",
      "coefficient": -3.114,
      "feature": 23.2126014075568,
      "product": -72.28404078313187
    },
    {
      "name": "hdl",
      "coefficient": -13.578,
      "feature": 3.58351893845611,
      "product": -48.657020146357056
    },
    {
      "name": "ageHdl",
      "coefficient": 3.149,
      "feature": 15.120685772460059,
      "product": 47.61503949747672
    },
    {
      "name": "sbpT",
      "coefficient": 2.019,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.957,
      "feature": 5.087596335232384,
      "product": 9.956426028049775
    },
    {
      "name": "smoke",
      "coefficient": 7.574,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.665,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.661,
      "feature": 1,
      "product": 0.661
    }
  ]
}

案例 6

reference-006

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔白人
年龄: 55 岁
总胆固醇: 213 mg/dL
HDL 胆固醇: 50 mg/dL
收缩压: 120 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicWhite",
  "ageYears": 55,
  "totalCholesterolMgDl": 213,
  "hdlCholesterolMgDl": 50,
  "systolicBpMmHg": 120,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 5.3844219979087145
}

实际结果

{
  "linearPredictor": 60.699546225197835,
  "meanPredictorSum": 61.18,
  "baselineSurvival": 0.9144,
  "centeredPredictor": -0.48045377480216445,
  "relativeHazard": 0.6185026671926364,
  "survivalLog": -0.05534805116071166,
  "tenYearProbability": 0.053844219979087116,
  "tenYearPercent": 5.384421997908712,
  "terms": [
    {
      "name": "age",
      "coefficient": 12.344,
      "feature": 4.007333185232471,
      "product": 49.466520838509624
    },
    {
      "name": "tc",
      "coefficient": 11.853,
      "feature": 5.3612921657094255,
      "product": 63.54739604015382
    },
    {
      "name": "ageTc",
      "coefficient": -2.664,
      "feature": 21.484484011374246,
      "product": -57.23466540630099
    },
    {
      "name": "hdl",
      "coefficient": -7.99,
      "feature": 3.912023005428146,
      "product": -31.257063813370888
    },
    {
      "name": "ageHdl",
      "coefficient": 1.769,
      "feature": 15.676779611045077,
      "product": 27.732223131938742
    },
    {
      "name": "sbpT",
      "coefficient": 1.797,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.764,
      "feature": 4.787491742782046,
      "product": 8.445135434267529
    },
    {
      "name": "smoke",
      "coefficient": 7.837,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.795,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.658,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 7

reference-007

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔白人
年龄: 40 岁
总胆固醇: 130 mg/dL
HDL 胆固醇: 100 mg/dL
收缩压: 90 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicWhite",
  "ageYears": 40,
  "totalCholesterolMgDl": 130,
  "hdlCholesterolMgDl": 100,
  "systolicBpMmHg": 90,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 0.09083943571466681
}

实际结果

{
  "linearPredictor": 56.590282464600136,
  "meanPredictorSum": 61.18,
  "baselineSurvival": 0.9144,
  "centeredPredictor": -4.589717535399863,
  "relativeHazard": 0.010155726601517827,
  "survivalLog": -0.0009088071973341058,
  "tenYearProbability": 0.0009083943571466583,
  "tenYearPercent": 0.09083943571466582,
  "terms": [
    {
      "name": "age",
      "coefficient": 12.344,
      "feature": 3.6888794541139363,
      "product": 45.535527981582426
    },
    {
      "name": "tc",
      "coefficient": 11.853,
      "feature": 4.867534450455582,
      "product": 57.69488584125001
    },
    {
      "name": "ageTc",
      "coefficient": -2.664,
      "feature": 17.955747826477367,
      "product": -47.83411220973571
    },
    {
      "name": "hdl",
      "coefficient": -7.99,
      "feature": 4.605170185988092,
      "product": -36.795309786044854
    },
    {
      "name": "ageHdl",
      "coefficient": 1.769,
      "feature": 16.987917681789526,
      "product": 30.05162637908567
    },
    {
      "name": "sbpT",
      "coefficient": 1.797,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.764,
      "feature": 4.499809670330265,
      "product": 7.937664258462587
    },
    {
      "name": "smoke",
      "coefficient": 7.837,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.795,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.658,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 8

reference-008

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔白人
年龄: 79 岁
总胆固醇: 320 mg/dL
HDL 胆固醇: 20 mg/dL
收缩压: 200 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicWhite",
  "ageYears": 79,
  "totalCholesterolMgDl": 320,
  "hdlCholesterolMgDl": 20,
  "systolicBpMmHg": 200,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 92.71522918124465
}

实际结果

{
  "linearPredictor": 64.5565993093616,
  "meanPredictorSum": 61.18,
  "baselineSurvival": 0.9144,
  "centeredPredictor": 3.376599309361602,
  "relativeHazard": 29.271059846601716,
  "survivalLog": -2.6193842061692774,
  "tenYearProbability": 0.9271522918124454,
  "tenYearPercent": 92.71522918124454,
  "terms": [
    {
      "name": "age",
      "coefficient": 12.344,
      "feature": 4.3694478524670215,
      "product": 53.93646429085291
    },
    {
      "name": "tc",
      "coefficient": 11.853,
      "feature": 5.768320995793772,
      "product": 68.37190876314358
    },
    {
      "name": "ageTc",
      "coefficient": -2.664,
      "feature": 25.204377787411527,
      "product": -67.14446242566432
    },
    {
      "name": "hdl",
      "coefficient": -7.99,
      "feature": 2.995732273553991,
      "product": -23.935900865696386
    },
    {
      "name": "ageHdl",
      "coefficient": 1.769,
      "feature": 13.089695949246632,
      "product": 23.15567213421729
    },
    {
      "name": "sbpT",
      "coefficient": 1.797,
      "feature": 5.298317366548036,
      "product": 9.52107630768682
    },
    {
      "name": "sbpU",
      "coefficient": 1.764,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 7.837,
      "feature": 1,
      "product": 7.837
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.795,
      "feature": 4.3694478524670215,
      "product": -7.843158895178303
    },
    {
      "name": "diabetes",
      "coefficient": 0.658,
      "feature": 1,
      "product": 0.658
    }
  ]
}

案例 9

reference-009

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔白人
年龄: 53.25 岁
总胆固醇: 197.5 mg/dL
HDL 胆固醇: 42.5 mg/dL
收缩压: 137.25 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicWhite",
  "ageYears": 53.25,
  "totalCholesterolMgDl": 197.5,
  "hdlCholesterolMgDl": 42.5,
  "systolicBpMmHg": 137.25,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 13.97317213396266
}

实际结果

{
  "linearPredictor": 61.699940857242645,
  "meanPredictorSum": 61.18,
  "baselineSurvival": 0.9144,
  "centeredPredictor": 0.5199408572426449,
  "relativeHazard": 1.6819281728874311,
  "survivalLog": -0.15051098645080205,
  "tenYearProbability": 0.1397317213396252,
  "tenYearPercent": 13.97317213396252,
  "terms": [
    {
      "name": "age",
      "coefficient": 12.344,
      "feature": 3.9749978045895347,
      "product": 49.06737289985321
    },
    {
      "name": "tc",
      "coefficient": 11.853,
      "feature": 5.285738584341177,
      "product": 62.65185944019596
    },
    {
      "name": "ageTc",
      "coefficient": -2.664,
      "feature": 21.01079926839037,
      "product": -55.97276925099195
    },
    {
      "name": "hdl",
      "coefficient": -7.99,
      "feature": 3.7495040759303713,
      "product": -29.958537566683667
    },
    {
      "name": "ageHdl",
      "coefficient": 1.769,
      "feature": 14.904270470122738,
      "product": 26.36565446164712
    },
    {
      "name": "sbpT",
      "coefficient": 1.797,
      "feature": 4.92180408038964,
      "product": 8.844481932460182
    },
    {
      "name": "sbpU",
      "coefficient": 1.764,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 7.837,
      "feature": 1,
      "product": 7.837
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.795,
      "feature": 3.9749978045895347,
      "product": -7.135121059238214
    },
    {
      "name": "diabetes",
      "coefficient": 0.658,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 10

reference-010

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔白人
年龄: 68 岁
总胆固醇: 245 mg/dL
HDL 胆固醇: 36 mg/dL
收缩压: 162 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicWhite",
  "ageYears": 68,
  "totalCholesterolMgDl": 245,
  "hdlCholesterolMgDl": 36,
  "systolicBpMmHg": 162,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 49.143687439623456
}

实际结果

{
  "linearPredictor": 63.20234328111665,
  "meanPredictorSum": 61.18,
  "baselineSurvival": 0.9144,
  "centeredPredictor": 2.0223432811166475,
  "relativeHazard": 7.556010060649815,
  "survivalLog": -0.6761659303846523,
  "tenYearProbability": 0.4914368743962319,
  "tenYearPercent": 49.14368743962319,
  "terms": [
    {
      "name": "age",
      "coefficient": 12.344,
      "feature": 4.219507705176107,
      "product": 52.08560311269386
    },
    {
      "name": "tc",
      "coefficient": 11.853,
      "feature": 5.501258210544727,
      "product": 65.20641356958666
    },
    {
      "name": "ageTc",
      "coefficient": -2.664,
      "feature": 23.2126014075568,
      "product": -61.83837014973132
    },
    {
      "name": "hdl",
      "coefficient": -7.99,
      "feature": 3.58351893845611,
      "product": -28.63231631826432
    },
    {
      "name": "ageHdl",
      "coefficient": 1.769,
      "feature": 15.120685772460059,
      "product": 26.74849313148184
    },
    {
      "name": "sbpT",
      "coefficient": 1.797,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.764,
      "feature": 5.087596335232384,
      "product": 8.974519935349925
    },
    {
      "name": "smoke",
      "coefficient": 7.837,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSmoke",
      "coefficient": -1.795,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.658,
      "feature": 1,
      "product": 0.658
    }
  ]
}

案例 11

reference-011

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 55 岁
总胆固醇: 213 mg/dL
HDL 胆固醇: 50 mg/dL
收缩压: 120 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 55,
  "totalCholesterolMgDl": 213,
  "hdlCholesterolMgDl": 50,
  "systolicBpMmHg": 120,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 3.026329344319297
}

实际结果

{
  "linearPredictor": 86.1676998549622,
  "meanPredictorSum": 86.61,
  "baselineSurvival": 0.9533,
  "centeredPredictor": -0.44230014503780524,
  "relativeHazard": 0.642556746290709,
  "survivalLog": -0.030730680869647385,
  "tenYearProbability": 0.030263293443192535,
  "tenYearPercent": 3.0263293443192536,
  "terms": [
    {
      "name": "age",
      "coefficient": 17.114,
      "feature": 4.007333185232471,
      "product": 68.58150013206851
    },
    {
      "name": "tc",
      "coefficient": 0.94,
      "feature": 5.3612921657094255,
      "product": 5.03961463576686
    },
    {
      "name": "hdl",
      "coefficient": -18.92,
      "feature": 3.912023005428146,
      "product": -74.01547526270053
    },
    {
      "name": "ageHdl",
      "coefficient": 4.475,
      "feature": 15.676779611045077,
      "product": 70.15358875942671
    },
    {
      "name": "sbpT",
      "coefficient": 29.291,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSbpT",
      "coefficient": -6.432,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 27.82,
      "feature": 4.787491742782046,
      "product": 133.1880202841965
    },
    {
      "name": "ageSbpU",
      "coefficient": -6.087,
      "feature": 19.18507453487693,
      "product": -116.77954869379586
    },
    {
      "name": "smoke",
      "coefficient": 0.691,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.874,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 12

reference-012

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 40 岁
总胆固醇: 130 mg/dL
HDL 胆固醇: 100 mg/dL
收缩压: 90 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 40,
  "totalCholesterolMgDl": 130,
  "hdlCholesterolMgDl": 100,
  "systolicBpMmHg": 90,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 0.013541761872041176
}

实际结果

{
  "linearPredictor": 80.74311423170191,
  "meanPredictorSum": 86.61,
  "baselineSurvival": 0.9533,
  "centeredPredictor": -5.86688576829809,
  "relativeHazard": 0.002831678118596184,
  "survivalLog": -0.00013542678851397982,
  "tenYearProbability": 0.0001354176187204061,
  "tenYearPercent": 0.013541761872040611,
  "terms": [
    {
      "name": "age",
      "coefficient": 17.114,
      "feature": 3.6888794541139363,
      "product": 63.13148297770591
    },
    {
      "name": "tc",
      "coefficient": 0.94,
      "feature": 4.867534450455582,
      "product": 4.575482383428247
    },
    {
      "name": "hdl",
      "coefficient": -18.92,
      "feature": 4.605170185988092,
      "product": -87.12981991889471
    },
    {
      "name": "ageHdl",
      "coefficient": 4.475,
      "feature": 16.987917681789526,
      "product": 76.02093162600812
    },
    {
      "name": "sbpT",
      "coefficient": 29.291,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSbpT",
      "coefficient": -6.432,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 27.82,
      "feature": 4.499809670330265,
      "product": 125.18470502858797
    },
    {
      "name": "ageSbpU",
      "coefficient": -6.087,
      "feature": 16.59925544030452,
      "product": -101.03966786513362
    },
    {
      "name": "smoke",
      "coefficient": 0.691,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.874,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 13

reference-013

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 79 岁
总胆固醇: 320 mg/dL
HDL 胆固醇: 20 mg/dL
收缩压: 200 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 79,
  "totalCholesterolMgDl": 320,
  "hdlCholesterolMgDl": 20,
  "systolicBpMmHg": 200,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 74.08866091261832
}

实际结果

{
  "linearPredictor": 89.95066072862288,
  "meanPredictorSum": 86.61,
  "baselineSurvival": 0.9533,
  "centeredPredictor": 3.340660728622879,
  "relativeHazard": 28.237778051195995,
  "survivalLog": -1.3504895104885228,
  "tenYearProbability": 0.7408866091261666,
  "tenYearPercent": 74.08866091261666,
  "terms": [
    {
      "name": "age",
      "coefficient": 17.114,
      "feature": 4.3694478524670215,
      "product": 74.7787305471206
    },
    {
      "name": "tc",
      "coefficient": 0.94,
      "feature": 5.768320995793772,
      "product": 5.422221736046145
    },
    {
      "name": "hdl",
      "coefficient": -18.92,
      "feature": 2.995732273553991,
      "product": -56.67925461564151
    },
    {
      "name": "ageHdl",
      "coefficient": 4.475,
      "feature": 13.089695949246632,
      "product": 58.57638937287867
    },
    {
      "name": "sbpT",
      "coefficient": 29.291,
      "feature": 5.298317366548036,
      "product": 155.19301398355853
    },
    {
      "name": "ageSbpT",
      "coefficient": -6.432,
      "feature": 23.150721438952043,
      "product": -148.90544029533956
    },
    {
      "name": "sbpU",
      "coefficient": 27.82,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSbpU",
      "coefficient": -6.087,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 0.691,
      "feature": 1,
      "product": 0.691
    },
    {
      "name": "diabetes",
      "coefficient": 0.874,
      "feature": 1,
      "product": 0.874
    }
  ]
}

案例 14

reference-014

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 53.25 岁
总胆固醇: 197.5 mg/dL
HDL 胆固醇: 42.5 mg/dL
收缩压: 137.25 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 53.25,
  "totalCholesterolMgDl": 197.5,
  "hdlCholesterolMgDl": 42.5,
  "systolicBpMmHg": 137.25,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 14.170063769070726
}

实际结果

{
  "linearPredictor": 87.7715834689829,
  "meanPredictorSum": 86.61,
  "baselineSurvival": 0.9533,
  "centeredPredictor": 1.1615834689828972,
  "relativeHazard": 3.194988437806031,
  "survivalLog": -0.15280233322771675,
  "tenYearProbability": 0.14170063769070293,
  "tenYearPercent": 14.170063769070293,
  "terms": [
    {
      "name": "age",
      "coefficient": 17.114,
      "feature": 3.9749978045895347,
      "product": 68.0281124277453
    },
    {
      "name": "tc",
      "coefficient": 0.94,
      "feature": 5.285738584341177,
      "product": 4.968594269280706
    },
    {
      "name": "hdl",
      "coefficient": -18.92,
      "feature": 3.7495040759303713,
      "product": -70.94061711660262
    },
    {
      "name": "ageHdl",
      "coefficient": 4.475,
      "feature": 14.904270470122738,
      "product": 66.69661035379924
    },
    {
      "name": "sbpT",
      "coefficient": 29.291,
      "feature": 4.92180408038964,
      "product": 144.16456331869293
    },
    {
      "name": "ageSbpT",
      "coefficient": -6.432,
      "feature": 19.564160414168633,
      "product": -125.83667978393265
    },
    {
      "name": "sbpU",
      "coefficient": 27.82,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSbpU",
      "coefficient": -6.087,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 0.691,
      "feature": 1,
      "product": 0.691
    },
    {
      "name": "diabetes",
      "coefficient": 0.874,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 15

reference-015

输入

已发表方程使用的性别: 女性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 68 岁
总胆固醇: 245 mg/dL
HDL 胆固醇: 36 mg/dL
收缩压: 162 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "female",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 68,
  "totalCholesterolMgDl": 245,
  "hdlCholesterolMgDl": 36,
  "systolicBpMmHg": 162,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 40.32688703677115
}

实际结果

{
  "linearPredictor": 88.98910430404895,
  "meanPredictorSum": 86.61,
  "baselineSurvival": 0.9533,
  "centeredPredictor": 2.3791043040489512,
  "relativeHazard": 10.79522928912219,
  "survivalLog": -0.5162886361613184,
  "tenYearProbability": 0.40326887036771386,
  "tenYearPercent": 40.32688703677139,
  "terms": [
    {
      "name": "age",
      "coefficient": 17.114,
      "feature": 4.219507705176107,
      "product": 72.2126548663839
    },
    {
      "name": "tc",
      "coefficient": 0.94,
      "feature": 5.501258210544727,
      "product": 5.1711827179120435
    },
    {
      "name": "hdl",
      "coefficient": -18.92,
      "feature": 3.58351893845611,
      "product": -67.8001783155896
    },
    {
      "name": "ageHdl",
      "coefficient": 4.475,
      "feature": 15.120685772460059,
      "product": 67.66506883175876
    },
    {
      "name": "sbpT",
      "coefficient": 29.291,
      "feature": 0,
      "product": 0
    },
    {
      "name": "ageSbpT",
      "coefficient": -6.432,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 27.82,
      "feature": 5.087596335232384,
      "product": 141.5369300461649
    },
    {
      "name": "ageSbpU",
      "coefficient": -6.087,
      "feature": 21.467151937338766,
      "product": -130.67055384258106
    },
    {
      "name": "smoke",
      "coefficient": 0.691,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.874,
      "feature": 1,
      "product": 0.874
    }
  ]
}

案例 16

reference-016

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 55 岁
总胆固醇: 213 mg/dL
HDL 胆固醇: 50 mg/dL
收缩压: 120 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 55,
  "totalCholesterolMgDl": 213,
  "hdlCholesterolMgDl": 50,
  "systolicBpMmHg": 120,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 6.0734372944925274
}

实际结果

{
  "linearPredictor": 18.9727973684095,
  "meanPredictorSum": 19.54,
  "baselineSurvival": 0.8954,
  "centeredPredictor": -0.5672026315905008,
  "relativeHazard": 0.5671096364558379,
  "survivalLog": -0.06265695686494871,
  "tenYearProbability": 0.0607343729449254,
  "tenYearPercent": 6.07343729449254,
  "terms": [
    {
      "name": "age",
      "coefficient": 2.469,
      "feature": 4.007333185232471,
      "product": 9.89410563433897
    },
    {
      "name": "tc",
      "coefficient": 0.302,
      "feature": 5.3612921657094255,
      "product": 1.6191102340442465
    },
    {
      "name": "hdl",
      "coefficient": -0.307,
      "feature": 3.912023005428146,
      "product": -1.2009910626664408
    },
    {
      "name": "sbpT",
      "coefficient": 1.916,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.809,
      "feature": 4.787491742782046,
      "product": 8.660572562692721
    },
    {
      "name": "smoke",
      "coefficient": 0.549,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.645,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 17

reference-017

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 40 岁
总胆固醇: 130 mg/dL
HDL 胆固醇: 100 mg/dL
收缩压: 90 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 40,
  "totalCholesterolMgDl": 130,
  "hdlCholesterolMgDl": 100,
  "systolicBpMmHg": 90,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 1.1742145762901328
}

实际结果

{
  "linearPredictor": 17.304207222773996,
  "meanPredictorSum": 19.54,
  "baselineSurvival": 0.8954,
  "centeredPredictor": -2.2357927772260027,
  "relativeHazard": 0.10690734254237061,
  "survivalLog": -0.011811629215271213,
  "tenYearProbability": 0.011742145762901298,
  "tenYearPercent": 1.17421457629013,
  "terms": [
    {
      "name": "age",
      "coefficient": 2.469,
      "feature": 3.6888794541139363,
      "product": 9.107843372207308
    },
    {
      "name": "tc",
      "coefficient": 0.302,
      "feature": 4.867534450455582,
      "product": 1.4699954040375858
    },
    {
      "name": "hdl",
      "coefficient": -0.307,
      "feature": 4.605170185988092,
      "product": -1.4137872470983441
    },
    {
      "name": "sbpT",
      "coefficient": 1.916,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.809,
      "feature": 4.499809670330265,
      "product": 8.140155693627449
    },
    {
      "name": "smoke",
      "coefficient": 0.549,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.645,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 18

reference-018

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 79 岁
总胆固醇: 320 mg/dL
HDL 胆固醇: 20 mg/dL
收缩压: 200 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 79,
  "totalCholesterolMgDl": 320,
  "hdlCholesterolMgDl": 20,
  "systolicBpMmHg": 200,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 96.54123982745598
}

实际结果

{
  "linearPredictor": 22.956085954795757,
  "meanPredictorSum": 19.54,
  "baselineSurvival": 0.8954,
  "centeredPredictor": 3.416085954795758,
  "relativeHazard": 30.44999880148351,
  "survivalLog": -3.3642599927692554,
  "tenYearProbability": 0.9654123982745598,
  "tenYearPercent": 96.54123982745598,
  "terms": [
    {
      "name": "age",
      "coefficient": 2.469,
      "feature": 4.3694478524670215,
      "product": 10.788166747741075
    },
    {
      "name": "tc",
      "coefficient": 0.302,
      "feature": 5.768320995793772,
      "product": 1.742032940729719
    },
    {
      "name": "hdl",
      "coefficient": -0.307,
      "feature": 2.995732273553991,
      "product": -0.9196898079810751
    },
    {
      "name": "sbpT",
      "coefficient": 1.916,
      "feature": 5.298317366548036,
      "product": 10.151576074306037
    },
    {
      "name": "sbpU",
      "coefficient": 1.809,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 0.549,
      "feature": 1,
      "product": 0.549
    },
    {
      "name": "diabetes",
      "coefficient": 0.645,
      "feature": 1,
      "product": 0.645
    }
  ]
}

案例 19

reference-019

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 53.25 岁
总胆固醇: 197.5 mg/dL
HDL 胆固醇: 42.5 mg/dL
收缩压: 137.25 mmHg
目前接受降压治疗？: 是
目前吸烟？: 是
糖尿病？: 否
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 53.25,
  "totalCholesterolMgDl": 197.5,
  "hdlCholesterolMgDl": 42.5,
  "systolicBpMmHg": 137.25,
  "treatedBp": "yes",
  "smoker": "yes",
  "diabetes": "no",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 19.923430017126194
}

实际结果

{
  "linearPredictor": 20.23864149871852,
  "meanPredictorSum": 19.54,
  "baselineSurvival": 0.8954,
  "centeredPredictor": 0.6986414987185192,
  "relativeHazard": 2.011018879211835,
  "survivalLog": -0.22218688428015398,
  "tenYearProbability": 0.19923430017126145,
  "tenYearPercent": 19.923430017126144,
  "terms": [
    {
      "name": "age",
      "coefficient": 2.469,
      "feature": 3.9749978045895347,
      "product": 9.81426957953156
    },
    {
      "name": "tc",
      "coefficient": 0.302,
      "feature": 5.285738584341177,
      "product": 1.5962930524710353
    },
    {
      "name": "hdl",
      "coefficient": -0.307,
      "feature": 3.7495040759303713,
      "product": -1.151097751310624
    },
    {
      "name": "sbpT",
      "coefficient": 1.916,
      "feature": 4.92180408038964,
      "product": 9.430176618026548
    },
    {
      "name": "sbpU",
      "coefficient": 1.809,
      "feature": 0,
      "product": 0
    },
    {
      "name": "smoke",
      "coefficient": 0.549,
      "feature": 1,
      "product": 0.549
    },
    {
      "name": "diabetes",
      "coefficient": 0.645,
      "feature": 0,
      "product": 0
    }
  ]
}

案例 20

reference-020

输入

已发表方程使用的性别: 男性
模型推导人群组别: 非西班牙裔非洲裔美国人
年龄: 68 岁
总胆固醇: 245 mg/dL
HDL 胆固醇: 36 mg/dL
收缩压: 162 mmHg
目前接受降压治疗？: 否
目前吸烟？: 否
糖尿病？: 是
既往心肌梗死？: 否
既往卒中？: 否
既往心力衰竭？: 否
既往经皮冠状动脉介入治疗？: 否
既往冠状动脉旁路移植术？: 否
既往心房颤动？: 否
已确认基线评估时表面健康的状态？: 是
已确认将此历史模型用于研究？: 是

{
  "sex": "male",
  "population": "nonHispanicAfricanAmerican",
  "ageYears": 68,
  "totalCholesterolMgDl": 245,
  "hdlCholesterolMgDl": 36,
  "systolicBpMmHg": 162,
  "treatedBp": "no",
  "smoker": "no",
  "diabetes": "yes",
  "priorMI": "no",
  "priorStroke": "no",
  "priorHF": "no",
  "priorPCI": "no",
  "priorCABG": "no",
  "atrialFibrillation": "no",
  "apparentlyHealthy": "yes",
  "historicalResearchConfirmed": "yes"
}

预期结果

{
  "tenYearPercent": 32.9969294153124
}

实际结果

{
  "linearPredictor": 20.82766595999367,
  "meanPredictorSum": 19.54,
  "baselineSurvival": 0.8954,
  "centeredPredictor": 1.2876659599936708,
  "relativeHazard": 3.6243173741463988,
  "survivalLog": -0.40043173802506704,
  "tenYearProbability": 0.3299692941531238,
  "tenYearPercent": 32.99692941531238,
  "terms": [
    {
      "name": "age",
      "coefficient": 2.469,
      "feature": 4.219507705176107,
      "product": 10.417964524079807
    },
    {
      "name": "tc",
      "coefficient": 0.302,
      "feature": 5.501258210544727,
      "product": 1.6613799795845077
    },
    {
      "name": "hdl",
      "coefficient": -0.307,
      "feature": 3.58351893845611,
      "product": -1.1001403141060258
    },
    {
      "name": "sbpT",
      "coefficient": 1.916,
      "feature": 0,
      "product": 0
    },
    {
      "name": "sbpU",
      "coefficient": 1.809,
      "feature": 5.087596335232384,
      "product": 9.203461770435382
    },
    {
      "name": "smoke",
      "coefficient": 0.549,
      "feature": 0,
      "product": 0
    },
    {
      "name": "diabetes",
      "coefficient": 0.645,
      "feature": 1,
      "product": 0.645
    }
  ]
}

代码与可复现性

代码许可证: MIT

此仓库的许可证适用于代码。第三方量表、问卷、数据和模型仍须遵守权利人的条件。

代码测试属于技术检查。临床批准和专业翻译审校分别记录。