Down syndrome risk by maternal age
Estimates live-birth Down syndrome prevalence by maternal age at delivery, the starting risk for counseling and prenatal screening.
Calculate with transparency
Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.
Preparing the form…
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Method · Limits of application
Morris–Mutton–Alberman 2002: England/Wales live-birth logistic model 1989–1998; not universal gestational risk
This formula describes Down syndrome prevalence in live births by maternal age, using England and Wales data from 1989–1998 and estimating the absence of screening and selective termination. It does not provide risk at every gestational age or replace individual screening or diagnosis.
Conditions of use
Check the population, units, inclusion and exclusion criteria, and version in the original source. A result alone does not establish a diagnosis, discharge decision or prescription.
Documented parameters
- Maternal age on the estimated due date · years
3/3 reference cases checked. Numerical tests are not clinical validation.
Relationship with cancer research
General context — relationship to be defined
A resource for general clinical contexts. This edition does not assign a specific oncological relationship; selecting it for a study requires a justified question, population and purpose.