Post-test probability (Bayes’ theorem)
Converts a disease’s pretest probability to probability after a test result using that result’s likelihood ratio.
Calculate with transparency
Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.
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Method · Limits of application
Bayes odds: Fagan 1975; pretest odds×LR, posttest conversion; Deeks–Altman 2004 likelihood ratios
Pre-test probability must represent the population and clinical context assessed; the likelihood ratio must correspond to the test and result category. Probability and odds are different quantities: updating multiplies odds by the likelihood ratio and only then converts back to probability. Predictive values vary with prevalence and do not transfer automatically between studies and services. The calculation updates an estimate; it does not independently confirm or exclude a disease.
Conditions of use
Check the population, units, inclusion and exclusion criteria, and version in the original source. A result alone does not establish a diagnosis, discharge decision or prescription.
Documented parameters
- Pretest probability (prevalence or clinical estimate) · %
- Likelihood ratio of the result (LR+ if positive, LR− if negative)
3/3 reference cases checked. Numerical tests are not clinical validation.
Relationship with cancer research
Support for research — context required
A general method for post-test probability. It requires pre-test probability and test performance applicable to the population; it is not a cancer detector.
Applications: Early detection and risk assessment · Clinical trials and methods