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BODE index

A 0–10 score combining BMI, FEV₁, dyspnoea (mMRC) and six-minute walk distance to estimate death risk in COPD.

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Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.

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Method · Limits of application

BODE/Celli 2004: BMI/FEV₁/mMRC/6MWD, total 0–10; original, not updated BODE

The original BODE was developed for prognosis in COPD using respiratory and systemic measures, including the six-minute walk. It does not diagnose COPD or automatically provide an individual probability for a time horizon; test conditions, item definitions and eligibility must match the version.

Conditions of use

Check the population, units, inclusion and exclusion criteria, and version in the original source. A result alone does not establish a diagnosis, discharge decision or prescription.

Documented parameters

Postbronchodilator FEV₁ · % of predicted
Six-minute walk test distance · m
Dyspnea (mMRC scale)
BMI · kg/m²

4/4 reference cases checked. Numerical tests are not clinical validation.

Sources and documentation

Documented formula

Transcribed from the source or a recorded revision; this is not a clinical recommendation.

O (FEV₁ % predicted): ≥ 65 = 0; 50–64 = 1; 36–49 = 2; ≤ 35 = 3.
E (6-minute walk): ≥ 350 m = 0; 250–349 = 1; 150–249 = 2; ≤ 149 = 3.
D (mMRC): 0–1 = 0; 2 = 1; 3 = 2; 4 = 3.
B (BMI): > 21 = 0; ≤ 21 = 1.

References

Celli BR et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med, 2004.

Identifier: indice-bode

Original clinical content: Brazilian Portuguese.

Method version

BODE/Celli 2004: BMI/FEV₁/mMRC/6MWD, total 0–10; original, not updated BODE

indice-bode@native-2026-10-03+c8f996e6a1bb

Source for the active edition

The bibliographic edition identifies the source. By itself, it proves neither full conformity of the formula nor clinical approval.

Synthetic cases checked (4)

Synthetic cases for checking the implementation, with no patient data.

Case 1

reference-001

Inputs

Postbronchodilator FEV₁: 70 % of predicted
Six-minute walk test distance: 400 m
Dyspnea (mMRC scale): 1: when hurrying or walking uphill
BMI: 25 kg/m²

{
  "vef1": 70,
  "dist": 400,
  "mmrc": "1",
  "imc": 25
}

Expected result

{
  "score": 0,
  "level": "low"
}

Actual result

{
  "score": 0,
  "q": 1
}

Case 2

reference-002

Inputs

Postbronchodilator FEV₁: 65 % of predicted
Six-minute walk test distance: 350 m
Dyspnea (mMRC scale): 2: walks slower than people of the same age or stops when walking on level ground
BMI: 21 kg/m²

{
  "vef1": 65,
  "dist": 350,
  "mmrc": "2",
  "imc": 21
}

Expected result

{
  "score": 2,
  "level": "low"
}

Actual result

{
  "score": 2,
  "q": 1
}

Case 3

reference-003

Inputs

Postbronchodilator FEV₁: 45 % of predicted
Six-minute walk test distance: 300 m
Dyspnea (mMRC scale): 2: walks slower than people of the same age or stops when walking on level ground
BMI: 22 kg/m²

{
  "vef1": 45,
  "dist": 300,
  "mmrc": "2",
  "imc": 22
}

Expected result

{
  "score": 4,
  "level": "mid"
}

Actual result

{
  "score": 4,
  "q": 2
}

Case 4

reference-004

Inputs

Postbronchodilator FEV₁: 30 % of predicted
Six-minute walk test distance: 140 m
Dyspnea (mMRC scale): 4: housebound or breathless when dressing
BMI: 20 kg/m²

{
  "vef1": 30,
  "dist": 140,
  "mmrc": "4",
  "imc": 20
}

Expected result

{
  "score": 10,
  "level": "high"
}

Actual result

{
  "score": 10,
  "q": 4
}

Code and reproducibility

This tool’s code on GitHub

Download code and tests

Sources, version and reproduction instructions

The code tests are technical checks. Clinical approval and professional translation review are recorded separately.

Relationship with cancer research

General context — relationship to be defined

A resource for general clinical contexts. This edition does not assign a specific oncological relationship; selecting it for a study requires a justified question, population and purpose.