PUBLIC LIBRARY / CALCULATOR

Framingham 2008 cardiovascular risk

Estimates cardiovascular risk using the continuous Framingham 2008 model in the publication’s population and variables. This historical edition applies neither LDL targets nor the PREVENT model.

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Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.

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Method · Limits of application

Framingham General CVD 2008; continuous lipid-based model, historical

Original population: ages 30–74 without cardiovascular disease. Does not represent PREVENT or the SBC 2025 guideline. Does not apply lipid targets or treatments. Local calibration requires checking.

Conditions of use

Check the conditions of application before calculating. The result presents the documented formula or criteria; it does not establish a diagnosis or prescription.

Scope of this implementation

Parameters in this edition

Sex
Age · years
Total cholesterol · mg/dL
HDL cholesterol · mg/dL
Systolic blood pressure · mmHg
Taking blood pressure medication?
Smoker?
Diabetes?
No established cardiovascular disease; use of the historical Framingham 2008 version confirmed?

Sources and documentation

Method version

Framingham General CVD 2008; continuous lipid-based model, historical

Formula and criteria

Ten-year risk = 100 × [1 − S₀^exp(ΣβX − mean)]. Sex-specific coefficients from the continuous model with age, total cholesterol, HDL, treated/untreated SBP, smoking and diabetes.

Population and limitations

Synthetic cases checked (2)

Synthetic cases for checking the implementation, with no patient data.

Case 1

reference-001

Inputs

Sex: Male
Age: 55 years
Total cholesterol: 200 mg/dL
HDL cholesterol: 45 mg/dL
Systolic blood pressure: 130 mmHg
Taking blood pressure medication?: No
Smoker?: No
Diabetes?: No
No established cardiovascular disease; use of the historical Framingham 2008 version confirmed?: Yes

{
  "sexo": "M",
  "idade": 55,
  "ct": 200,
  "hdl": 45,
  "pas": 130,
  "tratada": "0",
  "fumante": "0",
  "diabetes": "0",
  "contexto": "1"
}

Expected result

{
  "risk": 12.148639774148753,
  "linear": 24.07972983235777
}

Actual result

{
  "risk": 12.148639774148762,
  "linear": 24.079729832357774
}

Case 2

reference-002

Inputs

Sex: Female
Age: 55 years
Total cholesterol: 200 mg/dL
HDL cholesterol: 45 mg/dL
Systolic blood pressure: 130 mmHg
Taking blood pressure medication?: No
Smoker?: No
Diabetes?: No
No established cardiovascular disease; use of the historical Framingham 2008 version confirmed?: Yes

{
  "sexo": "F",
  "idade": 55,
  "ct": 200,
  "hdl": 45,
  "pas": 130,
  "tratada": "0",
  "fumante": "0",
  "diabetes": "0",
  "contexto": "1"
}

Expected result

{
  "risk": 6.616180425503274,
  "linear": 26.484139608241048
}

Actual result

{
  "risk": 6.616180425503249,
  "linear": 26.484139608241044
}

Source for the active edition

Framingham Heart Study · General CVD 10-year risk · original coefficients

Additional reading and history

Identifier: escore-de-risco-global

Original clinical content: Brazilian Portuguese.

Code and reproducibility

This tool’s code on GitHub

Download code and tests

Sources, version and reproduction instructions

The code tests are technical checks. Clinical approval and professional translation review are recorded separately.

Relationship with cancer research

General context — relationship to be defined

A resource for general clinical contexts. This edition does not assign a specific oncological relationship; selecting it for a study requires a justified question, population and purpose.