PUBLIC LIBRARY / CALCULATOR

Local anesthetic: protocol limit

Enter the mg/kg limit, mg cap and concentration defined in the applicable protocol. The tool performs a mathematical conversion; it does not select a safe limit for a medicine.

Calculate with transparency

Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.

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Method · Limits of application

Conversion of the limit documented in the protocol; no universal maximum

No drug limit is filled in or recommended automatically. Does not calculate individual toxicity or guarantee safety; mixtures and cumulative doses require specific assessment.

Conditions of use

Check the conditions of application before calculating. The result presents the documented formula or criteria; it does not establish a diagnosis or prescription.

Scope of this implementation

No drug limit is filled in or recommended automatically. Does not calculate individual toxicity or guarantee safety; mixtures and cumulative doses require specific assessment.

Parameters in this edition

Local anesthetic
Weight · kg
Protocol weight-based dose limit · mg/kg
Absolute protocol limit · mg
Solution concentration · %
Route, technique, population, formulation and product-label/protocol limits checked; absence of mixtures or other exposures confirmed?

Sources and documentation

Method version

Conversion of the limit documented in the protocol; no universal maximum

Formula and criteria

Entered mathematical limit = min(weight × mg/kg limit, mg cap); corresponding volume = mg limit/(concentration % × 10).

Population and limitations

No drug limit is filled in or recommended automatically. Does not calculate individual toxicity or guarantee safety; mixtures and cumulative doses require specific assessment.

Synthetic cases checked (3)

Synthetic cases for checking the implementation, with no patient data.

Case 1

reference-001

Inputs

Local anesthetic: Lidocaine without vasoconstrictor
Weight: 70 kg
Protocol weight-based dose limit: 4.5 mg/kg
Absolute protocol limit: 300 mg
Solution concentration: 1 %
Route, technique, population, formulation and product-label/protocol limits checked; absence of mixtures or other exposures confirmed?: Yes

{
  "droga": "lido",
  "peso": 70,
  "limite": 4.5,
  "teto": 300,
  "conc": 1,
  "contexto": "1"
}

Expected result

{
  "dose": 300,
  "vol": 30,
  "weightLimit": 315,
  "cap": 300
}

Actual result

{
  "dose": 300,
  "vol": 30,
  "weightLimit": 315,
  "cap": 300
}

Case 2

reference-002

Inputs

Local anesthetic: Lidocaine without vasoconstrictor
Weight: 40 kg
Protocol weight-based dose limit: 4.5 mg/kg
Absolute protocol limit: 300 mg
Solution concentration: 2 %
Route, technique, population, formulation and product-label/protocol limits checked; absence of mixtures or other exposures confirmed?: Yes

{
  "droga": "lido",
  "peso": 40,
  "limite": 4.5,
  "teto": 300,
  "conc": 2,
  "contexto": "1"
}

Expected result

{
  "dose": 180,
  "vol": 9,
  "weightLimit": 180,
  "cap": 300
}

Actual result

{
  "dose": 180,
  "vol": 9,
  "weightLimit": 180,
  "cap": 300
}

Case 3

reference-003

Inputs

Local anesthetic: Ropivacaine
Weight: 50 kg
Protocol weight-based dose limit: 2 mg/kg
Absolute protocol limit: 200 mg
Solution concentration: 0.2 %
Route, technique, population, formulation and product-label/protocol limits checked; absence of mixtures or other exposures confirmed?: Yes

{
  "droga": "ropi",
  "peso": 50,
  "limite": 2,
  "teto": 200,
  "conc": 0.2,
  "contexto": "1"
}

Expected result

{
  "dose": 100,
  "vol": 50,
  "weightLimit": 100,
  "cap": 200
}

Actual result

{
  "dose": 100,
  "vol": 50,
  "weightLimit": 100,
  "cap": 200
}

Source for the active edition

DailyMed · lidocaine HCl · formulation- and population-specific limits

Additional reading and history

Identifier: dose-maxima-anestesico-local

Original clinical content: Brazilian Portuguese.

Code and reproducibility

This tool’s code on GitHub

Download code and tests

Sources, version and reproduction instructions

The code tests are technical checks. Clinical approval and professional translation review are recorded separately.

Relationship with cancer research

General context — relationship to be defined

A resource for general clinical contexts. This edition does not assign a specific oncological relationship; selecting it for a study requires a justified question, population and purpose.