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2010 ACR/EULAR rheumatoid arthritis criteria

Classifies definite rheumatoid arthritis in a patient with clinical synovitis in at least one joint and no alternative diagnosis explaining it.

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Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.

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Method · Limits of application

ACR/EULAR 2010: 4 domains, total 0–10, cutoff≥6; context and exclusions required

The ACR/EULAR 2010 classification requires confirmed synovitis in at least one joint and no alternative diagnosis that better explains it before applying the ≥6/10 cutoff. It was developed for newly presenting undifferentiated inflammatory synovitis. The score alone, without these conditions, does not reproduce the classification criteria.

Conditions of use

Check the population, units, inclusion and exclusion criteria, and version in the original source. A result alone does not establish a diagnosis, discharge decision or prescription.

Documented parameters

Joint involvement (swelling or tenderness)
Serology (rheumatoid factor and anti-CCP)
Acute-phase reactants (CRP and ESR)
Symptom duration

3/3 reference cases checked. Numerical tests are not clinical validation.

Sources and documentation

Documented formula

Transcribed from the source or a recorded revision; this is not a clinical recommendation.

Sum of four domains (maximum 10): joints (0–5), serology (0–3), acute-phase reactants (0–1) and symptom duration (0–1). Score ≥ 6 = definite rheumatoid arthritis.

Large joints: shoulders, elbows, hips, knees and ankles. Small: MCP, PIP, 2nd–5th MTP, thumb IP and wrists.

References

Aletaha D et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum, 2010.

Identifier: criterios-acr-eular-artrite-reumatoide

Original clinical content: Brazilian Portuguese.

Method version

ACR/EULAR 2010: 4 domains, total 0–10, cutoff≥6; context and exclusions required

criterios-acr-eular-artrite-reumatoide@native-2026-10-03+427ee6e60a09

Source for the active edition

The bibliographic edition identifies the source. By itself, it proves neither full conformity of the formula nor clinical approval.

Synthetic cases checked (3)

Synthetic cases for checking the implementation, with no patient data.

Case 1

reference-001

Inputs

Joint involvement (swelling or tenderness): 4 to 10 small joints (with or without large joints)
Serology (rheumatoid factor and anti-CCP): At least one high-positive titer (> 3× the upper limit)
Acute-phase reactants (CRP and ESR): Abnormal CRP or ESR
Symptom duration: ≥ 6 weeks

{
  "artic": "3",
  "soro": "3",
  "fase": "1",
  "duracao": "1"
}

Expected result

{
  "score": 8,
  "level": "high"
}

Actual result

{
  "score": 8
}

Case 2

reference-002

Inputs

Joint involvement (swelling or tenderness): > 10 joints (at least 1 small joint)
Serology (rheumatoid factor and anti-CCP): Both negative
Acute-phase reactants (CRP and ESR): Abnormal CRP or ESR
Symptom duration: < 6 weeks

{
  "artic": "5",
  "soro": "0",
  "fase": "1",
  "duracao": "0"
}

Expected result

{
  "score": 6,
  "level": "high"
}

Actual result

{
  "score": 6
}

Case 3

reference-003

Inputs

Joint involvement (swelling or tenderness): 1 to 3 small joints (with or without large joints)
Serology (rheumatoid factor and anti-CCP): At least one low-positive titer (up to 3× the upper limit)
Acute-phase reactants (CRP and ESR): Both normal
Symptom duration: ≥ 6 weeks

{
  "artic": "2",
  "soro": "2",
  "fase": "0",
  "duracao": "1"
}

Expected result

{
  "score": 5,
  "level": "low"
}

Actual result

{
  "score": 5
}

Code and reproducibility

This tool’s code on GitHub

Download code and tests

Sources, version and reproduction instructions

The code tests are technical checks. Clinical approval and professional translation review are recorded separately.

Relationship with cancer research

General context — relationship to be defined

A resource for general clinical contexts. This edition does not assign a specific oncological relationship; selecting it for a study requires a justified question, population and purpose.