ELUCENIA
ELUCENIA
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Absolute neutrophil count

Converts the white-cell differential to absolute neutrophils, a basis for defining febrile neutropenia, adjusting chemotherapy and assessing infection risk.

Arithmetic checks are available. Independent clinical review is pending. Inclusion in the catalogue does not constitute clinical validation.

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Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.

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Method · Limits of application

ANC: leukocytes×(segmented+bands)/100; IDSA 2010 update/published 2011 context

The IDSA 2010/2011 reference addresses fever and chemotherapy-induced neutropenia in patients with cancer, with stratification depending on signs/symptoms, cancer, therapy and comorbidities. The calculated absolute count does not replace that assessment. The definition’s thresholds and units must be checked in the full guideline; the abstract read does not provide them.

Required fields: 0/2 completed

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/µL · range 10–500000
% · range 0–100
% · range 0–100

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Conditions of use

Check the population, units, inclusion and exclusion criteria, and version in the original source. A result alone does not establish a diagnosis, discharge decision or prescription.

Documented parameters

  • Total white blood cell count · /µL
  • Segmented neutrophils · %
  • Band neutrophils (optional) · %

5/5 reference cases checked. Numerical tests are not clinical validation.

Relationship with cancer research

Support for research — context required

Neutrophil quantification that may support the description of hematological toxicity. Classification and management depend on the protocol, population and clinical assessment.

Applications: Adverse effects and safety

Immunology

ANC was a hematological variable monitored in 157 patients with advanced NSCLC treated with nivolumab/pembrolizumab (Soyano et al., 2018). This tool provides only the absolute count from the white blood cell count and differential; it does not calculate NLR or survival models, or determine the benefit of immunotherapy.

DOI: 10.1186/s40425-018-0447-2

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