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BISAP score

Simple bedside score during the first 24 hours identifying acute pancreatitis patients at higher risk of in-hospital death, organ failure and necrosis.

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Check the population, units and version. The result shows the formula or classification; it does not make an automatic treatment decision.

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Method · Limits of application

BISAP/Wu 2008: 5 factors, first 24 h; BUN >25 mg/dL; age >60

The 2008 BISAP uses data from the first 24 hours of acute pancreatitis to stratify in-hospital mortality risk. BUN >25 mg/dL and age >60 years are score items, not minimum inclusion criteria. Assessment of necrosis, organ failure and applicability to subgroups depend on their respective sources; observed rates do not establish individual prognostic certainty.

Conditions of use

Check the population, units, inclusion and exclusion criteria, and version in the original source. A result alone does not establish a diagnosis, discharge decision or prescription.

Documented parameters

Urea > 53 mg/dL (BUN > 25 mg/dL)
Altered mental status (Glasgow < 15)
SIRS (2 or more criteria)
Age > 60 years
Pleural effusion on imaging

2/2 reference cases checked. Numerical tests are not clinical validation.

Sources and documentation

Documented formula

Transcribed from the source or a recorded revision; this is not a clinical recommendation.

1 point for each item within 24 hours: BUN >25 mg/dL (urea >53 mg/dL), Impaired mental status, SIRS, Age >60 years, Pleural effusion.

SIRS: ≥2 of temperature <36 or >38 °C, HR >90 bpm, RR >20 breaths/min or PaCO₂ <32 mmHg, leukocytes <4,000 or >12,000/mm³ or >10% bands.

References

Identifier: bisap

Original clinical content: Brazilian Portuguese.

Method version

BISAP/Wu 2008: 5 factors, first 24 h; BUN >25 mg/dL; age >60

bisap@native-2026-10-03+77733daf6e1d

Source for the active edition

The bibliographic edition identifies the source. By itself, it proves neither full conformity of the formula nor clinical approval.

Synthetic cases checked (2)

Synthetic cases for checking the implementation, with no patient data.

Case 1

reference-001

Inputs

Age > 60 years: Yes
SIRS (2 or more criteria): Yes
Urea > 53 mg/dL (BUN > 25 mg/dL): No
Altered mental status (Glasgow < 15): No
Pleural effusion on imaging: No

{
  "idade": true,
  "sirs": true,
  "bun": false,
  "mental": false,
  "derrame": false
}

Expected result

{
  "score": 2,
  "level": "low"
}

Actual result

{
  "score": 2
}

Case 2

reference-002

Inputs

Urea > 53 mg/dL (BUN > 25 mg/dL): Yes
SIRS (2 or more criteria): Yes
Pleural effusion on imaging: Yes
Altered mental status (Glasgow < 15): No
Age > 60 years: No

{
  "bun": true,
  "sirs": true,
  "derrame": true,
  "mental": false,
  "idade": false
}

Expected result

{
  "score": 3,
  "level": "high"
}

Actual result

{
  "score": 3
}

Code and reproducibility

This tool’s code on GitHub

Download code and tests

Sources, version and reproduction instructions

The code tests are technical checks. Clinical approval and professional translation review are recorded separately.

Relationship with cancer research

General context — relationship to be defined

A resource for general clinical contexts. This edition does not assign a specific oncological relationship; selecting it for a study requires a justified question, population and purpose.