01Available sources
Starting point
According to the NCI, resistance to targeted therapies can involve changes to the target or growth mechanisms that do not depend on it.
Sources for this section
- Targeted Therapy to Treat CancerNational Cancer Institute / NIH
02Under scientific review
What to investigate
How can the mechanism present in each tumor context and at different times during treatment be identified?
Sources for this section
- Targeted Therapy to Treat CancerNational Cancer Institute / NIH
LIMITATIONS AND CONTEXT
The scope of this reading
- The source describes general mechanisms. This edition does not include a systematic comparison of mechanisms or interventions to overcome them.
- A systematic review of supporting and opposing evidence has not yet been completed; the initial source selection is not exhaustive.
ORIGINAL READING
References and sources
- Targeted Therapy to Treat CancerNational Cancer Institute / NIH
- National Cancer Institute